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Press releaseGlobeNewswire· December 8, 2025

Menarini Group Presents Elacestrant (ORSERDU®) Phase 2 Combination Data in Patients with ER+, HER2- Metastatic Breast Cancer (mBC) at the 2025 San Antonio Breast Cancer Symposium

View original at globenewswire.com
Menarini Group Presents Elacestrant (ORSERDU®) Phase 2 Combination Data in Patients with ER+, HER2- Metastatic Breast Cancer (mBC) at the 2025 San Antonio Breast Cancer Symposium In addition, the expansive elacestrant clinical development program updates reinforce its potential as a backbone endocrine therapy in combin…
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  • The encouraging progression-free survival data increase our confidence in the role elacestrant could play as an endocrine therapy backbone in the combination setting

    80% confidence

  • Menarini remains deeply committed to fully exploring elacestrant's potential benefit across multiple ongoing trials in both early stage and metastatic breast cancer

    80% confidence

  • ELEVATE data demonstrate that elacestrant in combination with everolimus or abemaciclib shows consistent PFS benefit irrespective of ESR1 mutation status in ER+/HER2- mBC patients who experienced disease progression on endocrine therapy

    80% confidence

  • The safety profile of elacestrant in combination with everolimus or abemaciclib is consistent with the known safety profiles of each drug, with no new safety signals observed

    80% confidence

  • The extensive evidence for elacestrant spans monotherapy setting in EMERALD study, backed by two recent real-world data publications, and its growing potential in combination regimens

    80% confidence

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