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Source document· January 28, 2026

Stock market today: S&P 500 slips from record as Fed stands pat, Nasdaq rises before Big Tech earnings flurry

View original at finance.yahoo.com
Stock market today: S&P 500 slips from record as Fed stands pat, Nasdaq rises before Big Tech earnings flurry US stocks were little changed on Wednesday after the Federal Reserve held interest rates unchanged in its first policy decision of the year…
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  • Amazon should operate like the world's largest startup

    80% confidence
  • US is not losing credibility about inflation expectations despite gold rally

    80% confidence
  • ASML customers have started to really believe in sustainability of AI demand

    80% confidence
  • Amazon cuts are intended to reduce layers, increase ownership, and reduce bureaucracy

    80% confidence
  • Fed credibility on inflation expectations is right where it needs to be despite gold rally

    80% confidence
  • Nothing to share on DOJ probe today

    80% confidence
  • Trump not concerned about recent slide in US dollar

    80% confidence
  • Every advanced economy and democracy has independent central banking

    80% confidence
  • The Lisa Cook case is 'perhaps the most important legal case in the Fed's 113-year history'

    80% confidence
  • Amazon layoffs are not the beginning of recurring reductions every few months

    80% confidence
  • If Fed loses independence, it would be hard to restore credibility

    80% confidence
  • US always has a strong dollar policy

    80% confidence
  • Fed has not lost independence and will not lose it

    80% confidence
  • Trump could announce Powell's successor any day now

    80% confidence
  • Powell attending Supreme Court hearing was a mistake because it politicizes Fed

    80% confidence
  • Amazon has not created distinctive customer experience with right economic model for physical grocery stores

    80% confidence
  • US is absolutely not intervening to support the yen

    80% confidence
  • Agentic AI means the stage is set for sustained increase in data generated and stored for inferencing

    80% confidence
What we know · the intelligence behind this page
Live from the substrate
What we're seeing
Q4 2026 Clinical Catalyst Season: Big-Pharma Data Flow, Regulatory Milestones, and a Thin AI-Drug Fringe
October 2026 conferences (EASD, IGCS, NACFC, HFSA) are producing a dense run of late-stage readouts from Novo Nordisk, Lilly, Roche, Bayer, Vertex and Galderma. Regulatory milestones are scheduled behind them: the ivonescimab BLA PDUFA date on 2026-11-14, FDA acceptance of Roche's vamikibart BLA, and Scholar Rock's EMA resubmission. The AI-and-finance angle is peripheral. It consists of the AI-designed drug Rentosertib and QAIAx, a speculative microcap whose trial claims (the QIII pilot, anticipated 2027-01-01, and a patent update) are forecasts and filings rather than data, so they warrant skepticism.
Our read on the data ›
Signals we're tracking
EPKINLY Regulatory-Clinical Success Cascade
High probability of expanded label indications, additional combination approvals, and competitive positioning strength in follicular lymphoma market. Predicts positive commercial uptake and potential accelerated review for related indications.
Patterns we're watching ›
Where sources disagree
ING Group
Both facts record the same metric (shares_outstanding) for ING Group at the identical observation date (2025-12-31). FACT A states 2,902,437,688 shares; FACT B states 2,902 million shares (2,902,000,000). The difference is 437,688 shares (~0.015%). This is a genuine value conflict, though the discrepancy appears to result from FACT B rounding to the nearest million while FACT A provides the precise count.
We flag conflicts openly ›
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