BioNTech (BNTX) Q3 2025 Earnings Call Transcript

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• First potential launches of Pumitamig expected before end of decade (pre-2030)

  80% confidence

• T-cell response breadth correlates with activity in iNeST therapy; immune cell PD-L1 matters; signal observed in TMB-low patients

  80% confidence

• US COVID-19 vaccination rate at ~20% is in line with expectations

  80% confidence

• Management emphasized rigorous financial discipline and focus on long-term sustainable growth

  80% confidence

• We expect to report a loss for the 2025 financial year as we continue to invest in our transition to become a fully integrated commercial oncology company

  80% confidence

• COVID-19 vaccine business has stable market share and pricing with lower volumes vs prior year, performing within expectations

  80% confidence

• BioNTech is positioned as a fully integrated AI-tech bio company with AI capabilities addressing inter-patient heterogeneity and intra-tumor variability

  80% confidence

• First pivotal combination regimen decisions for Pumitamig expected based on data over next year

  80% confidence

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