(VIANEWS) – Another day of trading has ended and here’s today’s list of stocks that have had significant trading activity in the US session.

The three biggest winners today are Sorrento Therapeutics, AMC, and Hercules Technology Growth Capital.

The three biggest losers today are Pacific Biosciences of California, JD.com, and Alnylam Pharmaceuticals.

Winners today

1. Sorrento Therapeutics (SRNE) – 28.06%

Sorrento Therapeutics, Inc., a clinical stage and commercial biopharmaceutical company, develops therapies for cancer, autoimmune, inflammatory, viral, and neurodegenerative diseases. It operates through two segments, Sorrento Therapeutics and Scilex. The company provides cancer therapeutic by leveraging its proprietary G-MAB antibody library and targeted delivery modalities, which include chimeric antigen receptor T-cell therapy (CAR-T), dimeric antigen receptor T-cell therapy, and antibody drug conjugate, as well as bispecific antibody approach; and Sofusa, a drug delivery technology that deliver biologic directly into the lymphatic system. Its clinical programs in development include anti-CD38 CAR-T therapy for the treatment of multiple myeloma, as well as for amyloidosis and graft versus host disease. The company develops resiniferatoxin, a non-opioid-based TRPV1 agonist neurotoxin for late stage cancer and osteoarthritis knee pain treatment; and ZTlido, a lidocaine delivery system for the treatment of postherpetic neuralgia. It engages in the development of SEMDEXA, an injectable viscous gel formulation, which is Phase III trial for the treatment of sciatica, a pathology of low back pain; SP-103, an investigational non-aqueous lidocaine topical system undergoing clinical development in chronic low back pain condition; and SP-104, a novel low-dose delayed-release naltrexone hydrochloride formulation for the treatment of fibromyalgia. It has collaboration with SmartPharm Therapeutics Inc. to develop gene-encoded antibody vaccine to protect against COVID-19; Celularity, Inc. for initiating Phase I/II clinical study, including up to 94 patients with COVID-19; Mount Sinai Health System to develop COVI-SHIELD, an antibody therapy targeting SARS-CoV-2 infection; and Mayo Clinic for Phase Ib pilot study using sofusa lymphatic drug delivery technology to deliver Ipilimumab in patient with melanoma. The company was founded in 2006 and is based in San Diego, California.

NASDAQ ended the session with Sorrento Therapeutics rising 28.06% to $0.40 on Tuesday, after two consecutive sessions in a row of gains. NASDAQ slid 2.5% to $11,492.30, after two sequential sessions in a row of losses, on what was an all-around negative trend trading session today.

Earnings Per Share

As for profitability, Sorrento Therapeutics has a trailing twelve months EPS of $-1.3.

The company’s return on equity, which measures the profitability of a business relative to shareholder’s equity, for the twelve trailing months is negative -378.92%.

Growth Estimates Quarters

The company’s growth estimates for the present quarter and the next is 50% and 66%, respectively.

More news about Sorrento Therapeutics.

2. AMC (AMC) – 14.22%

AMC Entertainment Holdings, Inc., through its subsidiaries, engages in the theatrical exhibition business. The company owns, operates, or has interests in theatres in the United States and Europe. As of March 1, 2022, it operated approximately 950 theatres and 10,600 screens. The company was founded in 1920 and is headquartered in Leawood, Kansas.

NYSE ended the session with AMC rising 14.22% to $5.99 on Tuesday, after two consecutive sessions in a row of losses. NYSE fell 1.67% to $15,574.92, after four sequential sessions in a row of losses, on what was an all-around down trend trading session today.

Earnings Per Share

As for profitability, AMC has a trailing twelve months EPS of $-39.15.

Revenue Growth

Year-on-year quarterly revenue growth grew by 26.9%, now sitting on 4.09B for the twelve trailing months.

Volatility

AMC’s last week, last month’s, and last quarter’s current intraday variation average was a positive 3.06%, a negative 0.46%, and a positive 5.64%.

AMC’s highest amplitude of average volatility was 5.16% (last week), 6.12% (last month), and 5.64% (last quarter).

Volume

Today’s last reported volume for AMC is 66681500 which is 109.66% above its average volume of 31803800.

Stock Price Classification

According to the stochastic oscillator, a useful indicator of overbought and oversold conditions, AMC’s stock is considered to be oversold (<=20).

More news about AMC.

3. Hercules Technology Growth Capital (HTGC) – 7.69%

Hercules Capital, Inc. is a business development company. The firm specializing in providing venture debt, debt, senior secured loans, and growth capital to privately held venture capital-backed companies at all stages of development from startups, to expansion stage including select publicly listed companies and select special opportunity lower middle market companies that require additional capital to fund acquisitions, recapitalizations and refinancing and established-stage companies. The firm provides growth capital financing solutions for capital extension; management buy-out and corporate spin-out financing solutions; company, asset specific, or intellectual property acquisition financing; convertible, subordinated and/or mezzanine loans; domestic and international corporate expansion; vendor financing; revenue acceleration by sales and marketing development, and manufacturing expansion. It provides asset-based financing with a focus on cash flow; accounts receivable facilities; equipment loans or leases; equipment acquisition; facilities build-out and/or expansion; working capital revolving lines of credit; inventory. The firm also provides bridge financing to IPO or mergers and acquisitions or technology acquisition; dividend recapitalizations and other sources of investor liquidity; cash flow financing to protect against share price volatility; competitor acquisition; pre-IPO financing for extra cash on the balance sheet; public company financing to continue asset growth and production capacity; short-term bridge financing; and strategic and intellectual property acquisition financings. It also focuses on customized financing solutions, emerging growth, mid venture, and late venture financing. The firm invests primarily in structured debt with warrants and, to a lesser extent, in senior debt and equity investments. The firm generally seeks to invest in companies that have been operating for at least six to 12 months prior to the date of their investment. It prefers to invest in technology, energy technology, sustainable and renewable technology, and life sciences. Within technology the firm focuses on advanced specialty materials and chemicals; communication and networking, consumer and business products; consumer products and services, digital media and consumer internet; electronics and computer hardware; enterprise software and services; gaming; healthcare services; information services; business services; media, content and information; mobile; resource management; security software; semiconductors; semiconductors and hardware; and software sector. Within energy technology, it invests in agriculture; clean technology; energy and renewable technology, fuels and power technology; geothermal; smart grid and energy efficiency and monitoring technologies; solar; and wind. Within life sciences, the firm invests in biopharmaceuticals; biotechnology tools; diagnostics; drug discovery, development and delivery; medical devices and equipment; surgical devices; therapeutics; pharma services; and specialty pharmaceuticals. It also invests in educational services. The firm invests primarily in United States based companies and considers investment in the West Coast, Mid-Atlantic regions, Southeast and Midwest; particularly in the areas of software, biotech and information services. The firm prefers to invest between $10 million to $250 million in equity per transactions. It invests generally between $1 million to $40 million in companies focused primarily on business services, communications, electronics, hardware, and healthcare services. The firm invests primarily in private companies but also have investments in public companies. For equity investments, the firm seeks to represent a controlling interest in its portfolio companies which may exceed 25% of the voting securities of such companies. The firm seeks to invest a limited portion of its assets in equipment-based loans to early-stage prospective portfolio companies. These loans are generally for amounts up to $3 million but may be up to $15 million for certain energy technology venture investments. The firm allows certain debt investments have the right to convert a portion of the debt investment into equity. It also co-invests with other private equity firms. The firm seeks to exit its investments through initial public offering, a private sale of equity interest to a third party, a merger or an acquisition of the company or a purchase of the equity position by the company or one of its stockholders. The firm has structured debt with warrants which typically have maturities of between two and seven years with an average of three years; senior debt with an investment horizon of less than three years; equipment loans with an investment horizon ranging from three to four years; and equity related securities with an investment horizon ranging from three to seven years. The firm prefers to invest through its balance sheet capital. The firm formerly known as Hercules Technology Growth Capital, Inc. Hercules Capital, Inc. was founded in December 2003 and is based in Palo Alto, California with additional offices in Connecticut; Boston, Massachusetts; San Diego, California; Westport, Connecticut; Elmhurst, Illinois; Santa Monica, California; McLean, Virginia; New York, New York; Radnor, Pennsylvania; and Washington, District of Columbia and London, United Kingdom.

NYSE ended the session with Hercules Technology Growth Capital rising 7.69% to $16.24 on Tuesday while NYSE fell 1.67% to $15,574.92.

Earnings Per Share

As for profitability, Hercules Technology Growth Capital has a trailing twelve months EPS of $0.33.

PE Ratio

Hercules Technology Growth Capital has a trailing twelve months price to earnings ratio of 49.21. Meaning, the purchaser of the share is investing $49.21 for every dollar of annual earnings.

The company’s return on equity, which measures the profitability of a business relative to shareholder’s equity, for the twelve trailing months is 7.53%.

Growth Estimates Quarters

The company’s growth estimates for the present quarter and the next is 50% and 43.8%, respectively.

More news about Hercules Technology Growth Capital.

4. Smith & Nephew (SNN) – 5.51%

Smith & Nephew plc, together with its subsidiaries, develops, manufactures, markets, and sells medical devices worldwide. The company offers knee implant products for knee replacement procedures; hip implants for the reconstruction of hip joints; and trauma and extremities products that include internal and external devices used in the stabilization of severe fractures and deformity correction procedures. It also provides sports medicine joint repair products for surgeons, including instruments, technologies, and implants necessary to perform minimally invasive surgery of the joints, such as the repair of soft tissue injuries and degenerative conditions of the knee, hip, and shoulder, as well as meniscal repair systems. In addition, the company offers arthroscopic enabling technologies comprising fluid management equipment for surgical access, high-definition cameras, digital image capture, scopes, light sources, and monitors to assist with visualization inside the joints, radio frequency, electromechanical and mechanical tissue resection devices, and hand instruments for removing damaged tissue; and ear, nose, and throat solutions. Further, it provides advanced wound care products for the treatment and prevention of acute and chronic wounds, which comprise leg, diabetic and pressure ulcers, burns, and post-operative wounds; advanced wound bioactives, including biologics and other bioactive technologies for debridement and dermal repair/regeneration, as well as regenerative medicine products including skin, bone graft, and articular cartilage substitutes; and advanced wound devices, such as traditional and single-use negative pressure wound therapy, and hydrosurgery systems. It primarily serves the healthcare providers. Smith & Nephew plc was founded in 1856 and is headquartered in Watford, the United Kingdom.

NYSE ended the session with Smith & Nephew jumping 5.51% to $29.40 on Tuesday while NYSE dropped 1.67% to $15,574.92.

Earnings Per Share

As for profitability, Smith & Nephew has a trailing twelve months EPS of $1.02.

PE Ratio

Smith & Nephew has a trailing twelve months price to earnings ratio of 28.71. Meaning, the purchaser of the share is investing $28.71 for every dollar of annual earnings.

The company’s return on equity, which measures the profitability of a business relative to shareholder’s equity, for the twelve trailing months is 9.25%.

More news about Smith & Nephew.

5. General Mills (GIS) – 4.69%

General Mills, Inc. manufactures and markets branded consumer foods worldwide. The company operates in five segments: North America Retail; Convenience Stores & Foodservice; Europe & Australia; Asia & Latin America; and Pet. It offers ready-to-eat cereals, refrigerated yogurt, soup, meal kits, refrigerated and frozen dough products, dessert and baking mixes, bakery flour, frozen pizza and pizza snacks, snack bars, fruit and salty snacks, ice cream, nutrition bars, wellness beverages, and savory and grain snacks, as well as various organic products, including frozen and shelf-stable vegetables. It also supplies branded and unbranded food products to the North American foodservice and commercial baking industries; and manufactures and markets pet food products, including dog and cat food. The company markets its products under the Annie's, Betty Crocker, Bisquick, Blue Buffalo, Blue Basics, Blue Freedom, Bugles, Cascadian Farm, Cheerios, Chex, Cinnamon Toast Crunch, Cocoa Puffs, Cookie Crisp, EPIC, Fiber One, Food Should Taste Good, Fruit by the Foot, Fruit Gushers, Fruit Roll-Ups, Gardetto's, Go-Gurt, Gold Medal, Golden Grahams, Häagen-Dazs, Helpers, Jus-Rol, Kitano, Kix, Lärabar, Latina, Liberté, Lucky Charms, Muir Glen, Nature Valley, Oatmeal Crisp, Old El Paso, Oui, Pillsbury, Progresso, Raisin Nut Bran, Total, Totino's, Trix, Wanchai Ferry, Wheaties, Wilderness, Yoki, and Yoplait trademarks. It sells its products directly, as well as through broker and distribution arrangements to grocery stores, mass merchandisers, membership stores, natural food chains, e-commerce retailers, commercial and noncommercial foodservice distributors and operators, restaurants, convenience stores, and pet specialty stores, as well as drug, dollar, and discount chains. The company operates 466 leased and 392 franchise ice cream parlors. General Mills, Inc. was founded in 1866 and is headquartered in Minneapolis, Minnesota.

NYSE ended the session with General Mills rising 4.69% to $80.37 on Tuesday, after two consecutive sessions in a row of gains. NYSE dropped 1.67% to $15,574.92, after four consecutive sessions in a row of losses, on what was an all-around down trend exchanging session today.

Earnings Per Share

As for profitability, General Mills has a trailing twelve months EPS of $4.12.

PE Ratio

General Mills has a trailing twelve months price to earnings ratio of 19.51. Meaning, the purchaser of the share is investing $19.51 for every dollar of annual earnings.

The company’s return on equity, which measures the profitability of a business relative to shareholder’s equity, for the twelve trailing months is 28.16%.

Volume

Today’s last reported volume for General Mills is 6675370 which is 78.64% above its average volume of 3736680.

More news about General Mills.

6. HSBC (HSBC) – 4.49%

HSBC Holdings plc provides banking and financial services worldwide. The company operates through Wealth and Personal Banking, Commercial Banking, and Global Banking and Markets segments. The Wealth and Personal Banking segment offers retail banking and wealth products, including current and savings accounts, mortgages and personal loans, credit and debit cards, and local and international payment services; and wealth management services comprising insurance and investment products, global asset management services, investment management, and private wealth solutions. This segment serves personal banking and high net worth individuals. The Commercial Banking segment provides credit and lending, treasury management, payment, cash management, commercial insurance, and investment services; commercial cards; international trade and receivables finance services; foreign exchange products; capital raising services on debt and equity markets; and advisory services. It serves small and medium sized enterprises, mid-market enterprises, and corporates. The Global Banking and Markets segment offers financing, advisory, and transaction services; and credit, rates, foreign exchange, equities, money markets, and securities services; and engages in principal investment activities. It serves government, corporate and institutional clients, and private investors. HSBC Holdings plc was founded in 1865 and is headquartered in London, the United Kingdom.

NYSE ended the session with HSBC rising 4.49% to $39.01 on Tuesday while NYSE fell 1.67% to $15,574.92.

Earnings Per Share

As for profitability, HSBC has a trailing twelve months EPS of $1.47.

PE Ratio

HSBC has a trailing twelve months price to earnings ratio of 26.63. Meaning, the purchaser of the share is investing $26.63 for every dollar of annual earnings.

The company’s return on equity, which measures the profitability of a business relative to shareholder’s equity, for the twelve trailing months is 7.03%.

More news about HSBC.

7. HCI Group (HCI) – 4.36%

HCI Group, Inc., together with its subsidiaries, engages in the property and casualty insurance, reinsurance, real estate, and information technology businesses in Florida. It provides residential insurance products, such as homeowners, fire, flood, and wind-only insurance to homeowners, condominium owners, and tenants for properties, as well as offers reinsurance programs. The company also owns and operates waterfront properties and retail shopping centers, and an office building, as well as commercial properties for investment purposes. In addition, it designs and develops web-based applications and products for mobile devices, including SAMS, an online policy administration platform; Harmony, a policy administration platform; ClaimColony, an end-to-end claims management platform; and AtlasViewer, a mapping and data visualization platform. The company was formerly known as Homeowners Choice, Inc. and changed its name to HCI Group, Inc. in May 2013. HCI Group, Inc. was incorporated in 2006 and is headquartered in Tampa, Florida.

NYSE ended the session with HCI Group rising 4.36% to $52.40 on Tuesday while NYSE slid 1.67% to $15,574.92.

Earnings Per Share

As for profitability, HCI Group has a trailing twelve months EPS of $-0.55.

The company’s return on equity, which measures the profitability of a business relative to shareholder’s equity, for the twelve trailing months is negative -17.32%.

Revenue Growth

Year-on-year quarterly revenue growth grew by 27.7%, now sitting on 491.94M for the twelve trailing months.

Moving Average

HCI Group’s value is way higher than its 50-day moving average of $43.56 and above its 200-day moving average of $50.91.

Volume

Today’s last reported volume for HCI Group is 70444 which is 47.81% below its average volume of 134988.

More news about HCI Group.

8. Harsco Corporation (HSC) – 4.2%

Harsco Corporation provides environmental solutions for industrial and specialty waste streams worldwide. It operates through two segments, Harsco Environmental and Harsco Clean Earth. The Harsco Environmental segment offers on-site services for material logistics, product quality improvement, and resource recovery for iron, steel, and metals manufacturing; manufactures and sells industrial abrasives, roofing granules, aluminum dross, and scrap processing systems; and produces value-added downstream products from industrial waste-stream. The Harsco Clean Earth segment provides waste management services, including transportation, specialty waste processing, and recycling and beneficial reuse solutions for hazardous wastes, and soil and dredged materials. The company was founded in 1853 and is headquartered in Camp Hill, Pennsylvania.

NYSE ended the session with Harsco Corporation jumping 4.2% to $8.69 on Tuesday, following the last session’s upward trend. NYSE slid 1.67% to $15,574.92, after four consecutive sessions in a row of losses, on what was an all-around down trend exchanging session today.

Earnings Per Share

As for profitability, Harsco Corporation has a trailing twelve months EPS of $-0.55.

The company’s return on equity, which measures the profitability of a business relative to shareholder’s equity, for the twelve trailing months is negative -14.45%.

Earnings Before Interest, Taxes, Depreciation, and Amortization

Harsco Corporation’s EBITDA is 22.87.

Revenue Growth

Year-on-year quarterly revenue growth grew by 3.5%, now sitting on 1.88B for the twelve trailing months.

More news about Harsco Corporation.

9. HCC Insurance Holdings (HCC) – 4.15%

Warrior Met Coal, Inc. produces and exports non-thermal metallurgical coal for the steel industry. It operates two underground mines located in Alabama. The company sells its metallurgical coal to a customer base of blast furnace steel producers located primarily in Europe, South America, and Asia. It also sells natural gas, which is extracted as a byproduct from coal production. Warrior Met Coal, Inc. was incorporated in 2015 and is headquartered in Brookwood, Alabama.

NYSE ended the session with HCC Insurance Holdings rising 4.15% to $41.66 on Tuesday while NYSE dropped 1.67% to $15,574.92.

Earnings Per Share

As for profitability, HCC Insurance Holdings has a trailing twelve months EPS of $12.4.

PE Ratio

HCC Insurance Holdings has a trailing twelve months price to earnings ratio of 3.36. Meaning, the purchaser of the share is investing $3.36 for every dollar of annual earnings.

The company’s return on equity, which measures the profitability of a business relative to shareholder’s equity, for the twelve trailing months is 55.3%.

More news about HCC Insurance Holdings.

10. Fresenius Medical Care AG (FMS) – 3.85%

Fresenius Medical Care AG & Co. KGaA provides dialysis care and related dialysis care services in Germany, North America, and internationally. It offers dialysis treatment and related laboratory and diagnostic services through a network of outpatient dialysis clinics; materials, training, and patient support services comprising clinical monitoring, follow-up assistance, and arranging for delivery of the supplies to the patient's residence; and dialysis services under contract to hospitals in the United States for the hospitalized end-stage renal disease (ESRD) patients and for patients suffering from acute kidney failure. The company also develops, manufactures, and distributes dialysis products, including polysulfone dialyzers, hemodialysis machines, peritoneal dialysis cyclers, peritoneal dialysis solutions, hemodialysis concentrates, solutions and granulates, bloodlines, renal pharmaceuticals, and systems for water treatment; and non-dialysis products, such as acute cardiopulmonary and apheresis products. In addition, it develops, acquires, and in-licenses renal pharmaceuticals; offers renal medications and supplies to patients at homes or to dialysis clinics; and provides vascular, cardiovascular, endovascular specialty, vascular care ambulatory surgery center, and physician nephrology and cardiology services. The company sells its products to dialysis clinics, hospitals, and specialized treatment clinics directly, as well as through local sales forces, independent distributors, dealers, and sales agents. As of February 23, 2022, it operated 4,171 outpatient dialysis clinics in approximately 150 countries. Fresenius Medical Care AG & Co. KGaA was incorporated in 1996 and is headquartered in Bad Homburg, Germany.

NYSE ended the session with Fresenius Medical Care AG rising 3.85% to $20.75 on Tuesday while NYSE slid 1.67% to $15,574.92.

Earnings Per Share

As for profitability, Fresenius Medical Care AG has a trailing twelve months EPS of $2.39.

PE Ratio

Fresenius Medical Care AG has a trailing twelve months price to earnings ratio of 8.69. Meaning, the purchaser of the share is investing $8.69 for every dollar of annual earnings.

The company’s return on equity, which measures the profitability of a business relative to shareholder’s equity, for the twelve trailing months is 6.66%.

Stock Price Classification

According to the stochastic oscillator, a useful indicator of overbought and oversold conditions, Fresenius Medical Care AG’s stock is considered to be oversold (<=20).

Sales Growth

Fresenius Medical Care AG’s sales growth is 10.1% for the ongoing quarter and 9.6% for the next.

More news about Fresenius Medical Care AG.

Losers Today

1. Pacific Biosciences of California (PACB) – -12.42%

Pacific Biosciences of California, Inc. designs, develops, and manufactures sequencing systems to resolve genetically complex problems. The company provides PacBio's Systems, which conduct, monitor, and analyse biochemical sequencing reactions; consumable products, including single molecule real-time (SMRT) cells; and various reagent kits designed for specific workflow, such as template preparation kit to convert DNA into SMRTbell double-stranded DNA library formats, including molecular biology reagents, such as ligase, buffers, and exonucleases. It also offers binding kits, such as modified DNA polymerase used to bind SMRTbell libraries to the polymerase in preparation for sequencing; and sequencing kits comprise reagents required for on-instrument, real-time sequencing, including the phospholinked nucleotides. The company serves research institutions; commercial laboratories; genome centers; public health labs, hospitals and clinical research institutes, contract research organizations, and academic institutions; pharmaceutical companies; and agricultural companies. It markets its products through a direct sales force in North America and Europe, as well as through distribution partners in Asia, Europe, the Middle East, Africa, and Latin America. Pacific Biosciences of California, Inc. has a development and commercialization agreement with Invitae Corporation. The company was formerly known as Nanofluidics, Inc. and changed its name to Pacific Biosciences of California, Inc. in 2005. Pacific Biosciences of California, Inc. was incorporated in 2000 and is headquartered in Menlo Park, California.

NASDAQ ended the session with Pacific Biosciences of California dropping 12.42% to $9.15 on Tuesday, after two sequential sessions in a row of losses. NASDAQ dropped 2.5% to $11,492.30, after two sequential sessions in a row of losses, on what was an all-around negative trend trading session today.

Earnings Per Share

As for profitability, Pacific Biosciences of California has a trailing twelve months EPS of $-0.34.

The company’s return on equity, which measures the profitability of a business relative to shareholder’s equity, for the twelve trailing months is negative -40.78%.

Revenue Growth

Year-on-year quarterly revenue growth declined by 7.4%, now sitting on 136.97M for the twelve trailing months.

Moving Average

Pacific Biosciences of California’s worth is under its 50-day moving average of $10.07 and way higher than its 200-day moving average of $7.34.

Volume

Today’s last reported volume for Pacific Biosciences of California is 5133670 which is 25.66% above its average volume of 4085180.

Volatility

Pacific Biosciences of California’s last week, last month’s, and last quarter’s current intraday variation average was a positive 0.61%, a negative 0.39%, and a positive 4.21%.

Pacific Biosciences of California’s highest amplitude of average volatility was 4.64% (last week), 3.35% (last month), and 4.21% (last quarter).

More news about Pacific Biosciences of California.

2. JD.com (JD) – -11.05%

JD.com, Inc. provides supply chain-based technologies and services in the People's Republic of China. The company offers computers, communication, and consumer electronics products, as well as home appliances; and general merchandise products comprising food, beverage and fresh produce, baby and maternity products, furniture and household goods, cosmetics and other personal care items, pharmaceutical and healthcare products, books, automobile accessories, apparel and footwear, bags, and jewelry. It also provides online marketplace services for third-party merchants; marketing services; and omni-channel solutions to customers and offline retailers, as well as online healthcare services. In addition, the company develops, owns, and manages its logistics facilities and other real estate properties to support third parties; and provides asset management services for logistics property investors. Further, it provides integrated data, technology, business, and user management industry solutions to support the digitization of enterprises and institutions. The company was formerly known as 360buy Jingdong Inc. and changed its name to JD.com, Inc. in January 2014. JD.com, Inc. was incorporated in 2006 and is headquartered in Beijing, the People's Republic of China.

NASDAQ ended the session with JD.com sliding 11.05% to $47.16 on Tuesday, following the last session’s downward trend. NASDAQ slid 2.5% to $11,492.30, after two successive sessions in a row of losses, on what was an all-around bearish trend trading session today.

Earnings Per Share

As for profitability, JD.com has a trailing twelve months EPS of $4.89.

PE Ratio

JD.com has a trailing twelve months price to earnings ratio of 9.64. Meaning, the purchaser of the share is investing $9.64 for every dollar of annual earnings.

The company’s return on equity, which measures the profitability of a business relative to shareholder’s equity, for the twelve trailing months is 0.44%.

Revenue Growth

Year-on-year quarterly revenue growth grew by 11.4%, now sitting on 1.03T for the twelve trailing months.

More news about JD.com.

3. Alnylam Pharmaceuticals (ALNY) – -10.46%

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing, and commercializing novel therapeutics based on ribonucleic acid interference. The company's pipeline of investigational RNAi therapeutics focuses on genetic medicines, cardio-metabolic diseases, hepatic infectious diseases, and central nervous system (CNS)/ocular diseases. Its marketed products include ONPATTRO (patisiran), a lipid complex injection for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults; GIVLAARI for the treatment of adults with acute hepatic porphyria (AHP); and OXLUMO (lumasiran) for the treatment of primary hyperoxaluria type 1 (PH1). In addition, the company is developing givosiran for the treatment of adolescent patients with AHP; patisiran for the treatment of transthyretin amyloidosis, or ATTR amyloidosis, with cardiomyopathy; cemdisiran to treat complement-mediated diseases; ALN-AAT02 for the treatment of AAT deficiency-associated liver disease; ALN-HBV02 to treat chronic HBV infection; Zilebesiran to treat hypertension; and ALN-HSD to treat NASH. Further, it offers Fitusiran for the treatment of hemophilia and rare bleeding disorders, Inclisiran to treat hypercholesterolemia, lumasiran for the treatment of advanced PH1 and recurrent renal stones, and vutrisiran for the treatment of ATTR amyloidosis, which is in phase 3 clinical trial. Alnylam Pharmaceuticals, Inc. has strategic collaborations with Regeneron Pharmaceuticals, Inc. to discover, develop, and commercialize RNAi therapeutics for a range of diseases by addressing therapeutic targets expressed in the eye and CNS; and Sanofi Genzyme to discover, develop, and commercialize RNAi therapeutics. It also has license and collaboration agreements with Novartis AG; Vir Biotechnology, Inc.; Dicerna Pharmaceuticals, Inc.; Ionis Pharmaceuticals, Inc.; and PeptiDream, Inc. The company was founded in 2002 and is headquartered in Cambridge, Massachusetts.

NASDAQ ended the session with Alnylam Pharmaceuticals sliding 10.46% to $199.48 on Tuesday while NASDAQ slid 2.5% to $11,492.30.

Earnings Per Share

As for profitability, Alnylam Pharmaceuticals has a trailing twelve months EPS of $-7.55.

The company’s return on equity, which measures the profitability of a business relative to shareholder’s equity, for the twelve trailing months is negative -343.51%.

Sales Growth

Alnylam Pharmaceuticals’s sales growth is 21.1% for the present quarter and 47.5% for the next.

Yearly Top and Bottom Value

Alnylam Pharmaceuticals’s stock is valued at $199.48 at 16:32 EST, way under its 52-week high of $242.97 and way above its 52-week low of $117.58.

Growth Estimates Quarters

The company’s growth estimates for the present quarter and the next is 8.8% and 9%, respectively.

Revenue Growth

Year-on-year quarterly revenue growth grew by 40.9%, now sitting on 960.92M for the twelve trailing months.

More news about Alnylam Pharmaceuticals.

4. SmileDirectClub (SDC) – -9.98%

SmileDirectClub, Inc., an oral care company, offers clear aligner therapy treatment. The company manages the end-to-end process, which include marketing, aligner manufacturing, fulfillment, treatment by a doctor, and monitoring through completion of their treatment with a network of approximately 250 licensed orthodontists and general dentists through its teledentistry platform, SmileCheck in the United States, Puerto Rico, Canada, Australia, the United Kingdom, New Zealand, Ireland, Hong Kong, Germany, Singapore, France, Spain, and Austria. It also offers aligners, impression and whitening kits, whitening gels, and retainers; and toothbrushes, toothpastes, water flossers, SmileSpa, and various ancillary oral care products. The company was founded in 2014 and is headquartered in Nashville, Tennessee.

NASDAQ ended the session with SmileDirectClub sliding 9.98% to $0.53 on Tuesday, after four consecutive sessions in a row of losses. NASDAQ dropped 2.5% to $11,492.30, after two sequential sessions in a row of losses, on what was an all-around down trend exchanging session today.

Earnings Per Share

As for profitability, SmileDirectClub has a trailing twelve months EPS of $-2.334.

More news about SmileDirectClub.

5. Pinduoduo (PDD) – -9.92%

Pinduoduo Inc., through its subsidiaries, operates an e-commerce platform in the People's Republic of China. It operates Pinduoduo, a mobile platform that offers a range of products, including apparel, shoes, bags, mother and childcare products, food and beverages, fresh produce, electronic appliances, furniture and household goods, cosmetics and other personal care items, sports and fitness items, and auto accessories. The company was formerly known as Walnut Street Group Holding Limited and changed its name to Pinduoduo Inc. in July 2018. Pinduoduo Inc. was incorporated in 2015 and is headquartered in Shanghai, the People's Republic of China.

NASDAQ ended the session with Pinduoduo sliding 9.92% to $84.15 on Tuesday, after two consecutive sessions in a row of losses. NASDAQ fell 2.5% to $11,492.30, after two consecutive sessions in a row of losses, on what was an all-around down trend exchanging session today.

Earnings Per Share

As for profitability, Pinduoduo has a trailing twelve months EPS of $-0.93.

The company’s return on equity, which measures the profitability of a business relative to shareholder’s equity, for the twelve trailing months is 32.76%.

Volatility

Pinduoduo’s last week, last month’s, and last quarter’s current intraday variation average was a negative 0.88%, a positive 0.08%, and a positive 2.47%.

Pinduoduo’s highest amplitude of average volatility was 2.53% (last week), 2.65% (last month), and 2.47% (last quarter).

Yearly Top and Bottom Value

Pinduoduo’s stock is valued at $84.15 at 16:32 EST, way under its 52-week high of $106.38 and way higher than its 52-week low of $23.21.

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6. Fastly (FSLY) – -9.91%

Fastly, Inc. operates an edge cloud platform for processing, serving, and securing its customer's applications in the United States, the Asia Pacific, Europe, and internationally. The edge cloud is a category of Infrastructure as a Service that enables developers to build, secure, and deliver digital experiences at the edge of the internet. It is a programmable platform designed for web and application delivery. The company offers Compute@Edge; developer hub that includes solution library patterns and recipes, API and language references, change logs, and Fastly Fiddle solutions; device detection and geolocation, edge dictionaries, edge access control lists, and edge authentication services; full site delivery services, such as dynamic site acceleration, origin shield, instant purge, surrogate keys, real-time logging and stats, cloud optimizer, programmatic control, edge databases, content compression, reliability, and modern protocols and performance services; and streaming solutions and services, including live streaming, media shield, and origin connect. It also provides edge security solutions, such as DDoS protection and cloud, edge web application firewall (WAF), transport layer security (TLS), platform TLS, and compliance services; unified web application and API protection solutions that includes runtime self-application protection, advanced rate limiting, API and ATO protection, account takeover protection, bot protection, and next generation WAF. In addition, the company offers edge applications, such as load balancers and image optimizers; video on demand; and managed edge delivery services. It serves customers operating in digital publishing, media and entertainment, technology, online retail, travel and hospitality, and financial services industries. The company was formerly known as SkyCache, Inc. and changed its name to Fastly, Inc. in May 2012. Fastly, Inc. was incorporated in 2011 and is headquartered in San Francisco, California.

NYSE ended the session with Fastly sliding 9.91% to $14.32 on Tuesday, after two successive sessions in a row of losses. NYSE slid 1.67% to $15,574.92, after four sequential sessions in a row of losses, on what was an all-around negative trend exchanging session today.

Earnings Per Share

As for profitability, Fastly has a trailing twelve months EPS of $-0.93.

The company’s return on equity, which measures the profitability of a business relative to shareholder’s equity, for the twelve trailing months is negative -21.46%.

Volume

Today’s last reported volume for Fastly is 7337580 which is 70.51% above its average volume of 4303240.

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7. Virgin Galactic (SPCE) – -9.54%

Virgin Galactic Holdings, Inc. focuses on the development, manufacture, and operation of spaceships and related technologies for conducting commercial human spaceflight and flying commercial research and development payloads into space. It is also involved in the ground and flight testing, and post-flight maintenance of its spaceflight system vehicles. The company serves private individuals, researchers, and government agencies. Virgin Galactic Holdings, Inc. was founded in 2017 is headquartered in Las Cruces, New Mexico. Virgin Galactic Holdings, Inc. was a former subsidiary of Virgin Orbit Holdings, Inc.

NYSE ended the session with Virgin Galactic sliding 9.54% to $5.76 on Tuesday, after two sequential sessions in a row of gains. NYSE dropped 1.67% to $15,574.92, after four successive sessions in a row of losses, on what was an all-around down trend exchanging session today.

Earnings Per Share

As for profitability, Virgin Galactic has a trailing twelve months EPS of $-1.55.

The company’s return on equity, which measures the profitability of a business relative to shareholder’s equity, for the twelve trailing months is negative -53.97%.

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8. Celsius Holdings (CELH) – -8.81%

Celsius Holdings, Inc. develops, processes, markets, distributes, and sells functional drinks and liquid supplements in North America, Europe, Asia, and internationally. It offers various carbonated and non-carbonated functional energy drinks under the CELSIUS Originals name; dietary supplement in carbonated flavors, including apple jack'd, orangesicle, inferno punch, cherry lime, blueberry pomegranate, strawberry dragon fruit, tangerine grapefruit, and jackfruit under the CELSIUS HEAT name; and branched-chain amino acids functional energy drink that fuels muscle recovery under the CELSIUS BCCA+ENERGY name. The company also provides CELSIUS On-the-Go, a powdered form of the active ingredients in functional energy drinks in individual On-The-Go packets and canisters; and sparkling grapefruit, cucumber lime, and orange pomegranate, as well as pineapple coconut, watermelon berry, and strawberries and cream non-carbonated functional energy drinks under the CELSIUS Sweetened. It distributes its products through direct-to-store delivery distributors and direct to retailers, including supermarkets, convenience stores, drug stores, nutritional stores, and mass merchants, as well as health clubs, spas, gyms, the military, and e-commerce websites. The company was formerly known as Vector Ventures, Inc. and changed its name to Celsius Holdings, Inc. in January 2007. Celsius Holdings, Inc. was founded in 2004 and is headquartered in Boca Raton, Florida.

NASDAQ ended the session with Celsius Holdings falling 8.81% to $86.48 on Tuesday while NASDAQ fell 2.5% to $11,492.30.

Earnings Per Share

As for profitability, Celsius Holdings has a trailing twelve months EPS of $0.11.

PE Ratio

Celsius Holdings has a trailing twelve months price to earnings ratio of 786.18. Meaning, the purchaser of the share is investing $786.18 for every dollar of annual earnings.

The company’s return on equity, which measures the profitability of a business relative to shareholder’s equity, for the twelve trailing months is negative -28.51%.

Volatility

Celsius Holdings’s last week, last month’s, and last quarter’s current intraday variation average was a negative 0.09%, a negative 0.36%, and a positive 2.64%.

Celsius Holdings’s highest amplitude of average volatility was 1.44% (last week), 2.08% (last month), and 2.64% (last quarter).

Sales Growth

Celsius Holdings’s sales growth is 71.8% for the current quarter and 61.9% for the next.

Moving Average

Celsius Holdings’s worth is way below its 50-day moving average of $103.03 and under its 200-day moving average of $89.32.

Revenue Growth

Year-on-year quarterly revenue growth grew by 98.3%, now sitting on 579.89M for the twelve trailing months.

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9. Generac Holdlings (GNRC) – -8.48%

Generac Holdings Inc. designs, manufactures, and sells power generation equipment, energy storage systems, and other power products for the residential, and light commercial and industrial markets worldwide. The company offers engines, alternators, batteries, electronic controls, steel enclosures, and other components. It also provides residential automatic standby generators ranging in output from 7.5kW to 150kW; air-cooled engine residential standby generators ranging from 7.5kW to 26kW; liquid-cooled engine generators with outputs ranging from 22kW to 150kW; and Mobile Link, a remote monitoring system for home standby generators. In addition, the company offers various portable generators ranging in size from 800W to 17.5kW; outdoor power equipment, such as trimmers, field and brush mowers, log splitters, stump grinders, chipper shredders, lawn and leaf vacuums, pressure washers, and water pumps; and clean energy solution under the PWRcell and PWRview brands. Further, it provides light towers, mobile generators, and mobile energy storage systems; commercial mobile pumps and dust-suppression equipment; various gaseous-engine control systems and accessories; light-commercial standby generators ranging from 22kW to 150kW and related transfer switches providing three-phase power for small and mid-sized businesses; and industrial generators ranging in output from 10kW to 3,250kW used as emergency backup for healthcare, telecom, datacom, commercial office, retail, municipal, and manufacturing markets. Additionally, the company sells aftermarket service parts and product accessories to dealers. It distributes its products through independent residential dealers, industrial distributors and dealers, national and regional retailers, e-commerce partners, electrical, HVAC and solar wholesalers, catalogs, equipment rental companies and distributors, and solar installers; and directly to end users. The company was founded in 1959 and is headquartered in Waukesha, Wisconsin.

NYSE ended the session with Generac Holdlings sliding 8.48% to $116.02 on Tuesday while NYSE dropped 1.67% to $15,574.92.

Earnings Per Share

As for profitability, Generac Holdlings has a trailing twelve months EPS of $7.12.

PE Ratio

Generac Holdlings has a trailing twelve months price to earnings ratio of 16.28. Meaning, the purchaser of the share is investing $16.28 for every dollar of annual earnings.

The company’s return on equity, which measures the profitability of a business relative to shareholder’s equity, for the twelve trailing months is 22.72%.

Stock Price Classification

According to the stochastic oscillator, a useful indicator of overbought and oversold conditions, Generac Holdlings’s stock is considered to be overbought (>=80).

Yearly Top and Bottom Value

Generac Holdlings’s stock is valued at $116.02 at 16:32 EST, way under its 52-week high of $329.50 and way higher than its 52-week low of $86.29.

Moving Average

Generac Holdlings’s value is higher than its 50-day moving average of $108.42 and way below its 200-day moving average of $175.54.

More news about Generac Holdlings.

10. DISH Network (DISH) – -8.41%

DISH Network Corporation, together with its subsidiaries, provides pay-TV services in the United States. The company operates in two segments, Pay-TV and Wireless. It offers video services under the DISH TV brand; and programming packages that include programming through national broadcast networks, local broadcast networks, and national and regional cable networks, as well as regional and specialty sports channels, premium movie channels, and Latino and international programming packages. The company also provides access to movies and television shows through TV or Internet-connected devices; and dishanywhere.com and mobile applications on Internet-connected devices to view authorized content, search program listings, and remotely control certain features of their DVRs. In addition, it offers Sling TV services, including Sling domestic, Sling International, Sling Latino, Sling Orange, and Sling Blue services that require an Internet connection and are available on streaming-capable devices, such as streaming media devices, TVs, tablets, computers, game consoles, and phones, as well as market SLING TV services to consumers who do not subscribe to traditional satellite and cable pay-TV services. Further, the company provides wireless subscribers consumer plans with no annual service contracts, as well as monthly service plans, including high-speed data and unlimited talk and text. As of December 31, 2021, it had 10.707 million pay-TV subscribers in the United States, including 8.221 million DISH TV subscribers and 2.486 million SLING TV subscribers. The company offers receiver systems and programming through direct sales channels, as well as independent third parties, such as small retailers, direct marketing groups, local and regional consumer electronics stores, retailers, and telecommunications companies. DISH Network Corporation was founded in 1980 and is headquartered in Englewood, Colorado.

NASDAQ ended the session with DISH Network sliding 8.41% to $12.96 on Tuesday while NASDAQ dropped 2.5% to $11,492.30.

Earnings Per Share

As for profitability, DISH Network has a trailing twelve months EPS of $3.88.

PE Ratio

DISH Network has a trailing twelve months price to earnings ratio of 3.34. Meaning, the purchaser of the share is investing $3.34 for every dollar of annual earnings.

The company’s return on equity, which measures the profitability of a business relative to shareholder’s equity, for the twelve trailing months is 12.11%.

More news about DISH Network.

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