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News articleSeeking Alpha· March 1, 2026

Jefferies updates its AI Risk Basket

View original at seekingalpha.com
Jefferies updates its AI Risk Basket [Hand pointing at digital warning icon with AI and data interface, representing system warning alert, cybersecurity threat, data error, and artificial intelligence risk.] Saksit Sangtong The Jefferies AI Risk Basket used to identify potential decliners from the impact of AI, is down…
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  • AI summaries reduce research value for Gartner

    80% confidence
  • AI reallocates performance ad spend away from Snap

    80% confidence
  • AI agents bypass OTAs for Expedia Group and Booking Holdings

    80% confidence
  • LLM agents replace RPA for UiPath

    80% confidence
  • AI copilots commoditize ticketing for Atlassian

    80% confidence
  • AI agents bypass listings for Zillow Group

    80% confidence
  • AI automates tax preparation for Intuit

    80% confidence
  • AI fears compress allocator fees for StepStone Group

    80% confidence
  • AI commoditizes email personalization for Klaviyo

    80% confidence
  • AI replicates data and cuts pricing for CoStar Group

    80% confidence
  • AI copilots reduce seat pricing for Workday

    80% confidence
  • The starting point is the sub-industries that could be impacted by various disruption vectors. We then combine this with stock-level returns and run it through a series of pre-trained prompts to obtain the stock-specific potential risk and disruption vector

    80% confidence
  • AI automates delivery labor for EPAM Systems

    80% confidence
  • AI fears compress private equity fees and multiples for alternative asset managers

    80% confidence
  • Ironically, we use an AI-assisted search algorithm to identify our AI-risk basket

    80% confidence
  • AI agents bypass CRM workflows for Salesforce

    80% confidence
  • AI content lowers switching costs for Unity Software

    80% confidence
  • Generative tools commoditize design for Adobe

    80% confidence

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What we know · the intelligence behind this page
Live from the substrate
What we're seeing
Pharma Pipeline Catalysts and M&A Heat Up as AI-Designed Drugs Enter the Clinic
Late-September 2026 brought a dense run of clinical readouts: Novo Nordisk's CagriSema data at EASD, Lilly's ADtouch results for EBGLYSS, and Merck's tulisokibart Phase 2b result. Lilly's $2.9B Merida Biosciences acquisition and the 2026-11-14 FDA PDUFA date for ivonescimab sit alongside these as the main deal and regulatory events. AI-designed drugs such as rentosertib, and speculative AI-linked trial ventures such as QAIAx, are moving from hype toward clinical validation. Broader AI-sector regulatory and legal friction (Tesla Cybercab probe, xAI Minnesota ruling, OpenAI lawsuits) shows rising scrutiny that could spill into AI-driven healthcare.
Our read on the data ›
Signals we're tracking
Satellite-Terrestrial Network Integration Acceleration
Increased investment and launches in hybrid satellite-cellular networks across telecom industry; competitive responses from other carriers; regulatory activity around satellite spectrum; expansion of emergency/rural connectivity use cases
Patterns we're watching ›
Where sources disagree
Apple Inc.
The observation date (2025-12-27) precedes Q1 2026, making it logically impossible to have actual Q1 2026 cash data at that point. Q1 2026 would not end until March 31, 2026. Additionally, the magnitude of the difference ($45.3B vs $132.42) is implausibly large even as a normal quarterly change for Apple. While different fiscal periods can show different values, the timing relationship here suggests a data integrity issue rather than legitimate period-over-period variation.
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